Polycystic ovary syndrome (PCOS) is the most common endocrine condition affecting approximately 5-10% of women of reproductive age in the world. PCOS affects how the ovaries work and can have symptoms such as irregular periods, increased hair growth due to higher testosterone levels, and polycystic ovaries. For those diagnosed with PCOS, starting a family can present unique challenges, although many can get pregnant naturally. At Apricity, the world's first virtual fertility clinic, we offer advanced IVF treatments specifically tailored to address the complexities of PCOS. This blog will provide an overview of PCOS, explain why IVF is a viable fertility treatment for those with this condition, and offer guidance on how to optimise your chances of success.

Understanding PCOS

PCOS is a hormonal disorder affecting women of reproductive age. Women with PCOS may experience:

• Irregular menstrual cycles

• Excess androgen levels, leading to symptoms like excess facial and body hair

• Multiple cysts on the ovaries

For more detailed information on PCOS, visit our PCOS and fertility guide.

Why IVF is effective for PCOS

It’s important to point out that, while not all women with PCOS will require IVF or assistance to conceive, many may benefit from fertility treatments. About 70-80% of women with PCOS experience infertility due to absence of ovulation (when a mature egg is not produced during menstrual cycle). Lifestyle changes, such as weight loss, diet, and exercise, can improve ovulation, as well as taking medications like clomiphene citrate (Clomid) or letrozole (Femara) that are often used as first-line treatments to induce ovulation.

If ovulation induction medications are not successful, treatments like intrauterine insemination (IUI) or IVF may be recommended. IVF is particularly useful for women with PCOS who do not respond to other treatments or have additional fertility factors (e.g., male infertility). Approximately 20-30% of women with PCOS may need IVF to conceive. 

1. Controlled ovarian stimulation

One of the steps leading to IVF is controlled ovarian stimulation, which is particularly beneficial for women with PCOS. Medications can be carefully managed to stimulate the ovaries to produce multiple eggs without overstimulating them, reducing the risk of ovarian hyperstimulation syndrome (OHSS).

2. High success rates

For women with PCOS, IVF often has the same success rates as for patients without PCOS undergoing fertility treatment. At Apricity, our success rates are 51% chance of live birth per embryo transferred compared to 27% national rate. This is thanks to our personalised approach and advanced algorithms guiding clinical decisions.

3. Monitoring and support

With the Apricity app, you receive 24/7 support and access to your treatment plan. Our technology ensures you never miss an injection or appointment, providing peace of mind throughout your IVF journey. Our dedicated fertility advisors are always available to answer any questions and provide guidance.

Is IVF successful with PCOS?

IVF can be really beneficial for women with PCOS. Studies have shown that the success rates for IVF in women with PCOS are as high as those without the condition. In general, women with PCOS undergoing fertility treatment can have as high as 55% pregnancy rates, especially when managed by experienced fertility specialists. 1 At Apricity, we tailor each treatment plan to your specific needs, optimising your chances of a successful pregnancy.

Lifestyle changes to improve IVF success with PCOS

1. Maintain a healthy weight

Weight management is crucial for women with PCOS undergoing IVF. Excess weight can affect hormone levels and ovulation. Losing even a small amount of weight can improve fertility and chances of success. For tips on losing weight and fertility, visit our weight loss and fertility blog.

2. Eat a balanced diet

A balanced diet can help regulate insulin levels and improve ovulation. Focus on a diet rich in fruits, vegetables, lean proteins, and whole grains. Avoiding processed foods and sugars can also help manage PCOS symptoms.

3. Regular exercise

Regular physical activity can improve insulin sensitivity and help with weight management. Activities such as walking, swimming, and yoga are excellent choices for women with PCOS.

4. Manage stress

Stress can negatively impact fertility. Techniques such as mindfulness, yoga, and meditation can help manage stress levels. Apricity’s mobile app provides tools and resources to help you stay organised and reduce anxiety throughout your IVF journey.

Does PCOS affect egg quality in IVF?

PCOS can disrupt the normal development of eggs in the ovaries. The hormonal imbalances that characterise PCOS can lead to eggs that are less mature or have genetic abnormalities, thus affecting their quality and the chances of successful fertilisation. Controlled ovarian stimulation during IVF can help produce mature eggs, increasing the chances of successful fertilisation and embryo development.

Why does IVF fail with PCOS?

IVF may fail with PCOS due to various factors, including:

• Poor egg quality: while PCOS doesn't directly impact egg quality, the hormonal imbalances can affect egg development.

• Insulin resistance: common in women with PCOS, it can affect the uterine environment and implantation.

• Embryo quality: not all embryos will be viable for implantation.

However, tailored treatment plans, close monitoring, and lifestyle modifications can significantly improve the chances of success.

What are the chances of getting pregnant with PCOS with IVF?

IVF success rates for women with PCOS are generally comparable to those of women with other infertility causes. Success rates vary depending on individual circumstances such as age, overall health, and the specific IVF protocol used. At Apricity, we are dedicated to maximising your chances of a successful pregnancy through personalised treatment plans and continuous support.

Conclusion

IVF is a promising fertility treatment for women with PCOS, offering higher success rates and the ability to manage ovarian stimulation effectively. At Apricity, we provide a unique, technology-driven approach to IVF, ensuring personalised care and support throughout your journey. By making lifestyle changes and following your tailored treatment plan, you can enhance your chances of a successful pregnancy.

Explore our IVF treatment packages and learn more about how we can help you on your fertility journey. For additional information on PCOS and fertility, visit our PCOS guide.